Nature Neuroscience publication

Our study “Tonic and burst-like locus coeruleus stimulation distinctly shift network activity across the cortical hierarchy” has been published in Nature Neuroscience. By combining optogenetics with functional brain imaging, we find that during moderate tonic locus coeruleus activation in mice, noradrenaline release engages cortical regions related to associative processing. In contrast, burst-like stimulation biases the brain toward sensory processing.